I use this guide to help B2B buyers verify the identity of 4-(Hydroxymethyl)phenylboronic acid, CAS 59016-93-2, assess whether it fits a synthetic route, and prepare a practical supplier inquiry. The compound is an aromatic boronic acid containing both a boronic acid group and a hydroxymethyl group, which gives it two useful functional handles for further chemical transformation. Its commonly listed molecular formula is C7H9BO3, with a molecular weight of approximately 151.96 g/mol.
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For procurement, I recommend confirming the CAS number, molecular formula, molecular weight, purity method, water content, residual solvents, packaging, and lot-specific documentation before placing an order. A catalog description alone is not enough for regulated, medicinal chemistry, or scale-up work. Maison Chemical can support buyers by reviewing technical requirements, arranging samples where available, and preparing a quotation based on grade, quantity, packaging, and delivery destination.
This guide is intended for procurement teams, process chemists, medicinal chemistry researchers, custom synthesis companies, and distributors sourcing organic boronic acids. It is also useful for buyers comparing suppliers that list the same CAS number but provide different purity levels, analytical packages, or fulfillment conditions. I focus on practical purchasing decisions rather than treating a database entry as a complete quality specification.
The compound may be purchased for laboratory research, route development, intermediate preparation, or evaluation in a larger synthetic program. The correct purchase decision depends on the intended reaction, the required scale, the buyer’s internal quality standard, and the level of documentation needed. Buyers should therefore define the use case before comparing price alone.
4-(Hydroxymethyl)phenylboronic acid is an aryl boronic acid with a hydroxymethyl substituent positioned on the aromatic ring. The boronic acid group is commonly used as a coupling partner in palladium-catalyzed carbon–carbon bond-forming reactions, particularly Suzuki-type chemistry. The hydroxymethyl group can also participate in protection, oxidation, etherification, esterification, or other downstream transformations, subject to the selected reaction conditions.
These two functional groups create useful synthetic flexibility, but they also require careful handling during method development. Boronic acids can show sensitivity to moisture, pH, heat, and storage conditions depending on their structure and formulation. I therefore recommend that buyers confirm the supplier’s storage guidance and review the lot-specific analytical data rather than assuming that every package will behave identically in every application.
When I evaluate this material for procurement, I separate confirmed identity from application suitability. The identity section should include the product name, CAS 59016-93-2, molecular formula, approximate molecular weight of 151.96 g/mol, and a clear description of the chemical form. The quality section should state the assay or purity method, typically supported by chromatographic or spectroscopic data where applicable.
| Specification Area | What I Ask the Supplier to Confirm | Why It Matters |
|---|---|---|
| Identity | CAS number, formula, molecular weight, and identity test | Prevents confusion with positional isomers or related boronic acids |
| Purity | Assay method, reported purity, and chromatogram when available | Shows whether the material matches the intended synthetic use |
| Impurities | Water, residual solvents, inorganic residues, and related substances | Impurities may affect reaction conversion, isolation, or reproducibility |
| Physical form | Appearance, packaging, storage recommendation, and batch information | Supports receiving inspection and laboratory handling |
| Documentation | COA, SDS, specification sheet, and available analytical data | Provides traceability for internal qualification and purchasing review |
Buyers should avoid treating “high purity” as a complete specification unless the numerical value and test method are stated. For example, a buyer may request a purity target of at least 98%, but that target must be agreed in writing and linked to a defined analytical method. I do not recommend presenting any purity value as a guaranteed product result unless it appears on the applicable batch certificate.
For medicinal chemistry and discovery synthesis, this compound may be considered when a project needs an aryl boronic acid together with a protected or transformable hydroxymethyl substituent. The boronic acid can support carbon–carbon bond construction, while the hydroxymethyl group may be modified before or after coupling. The best grade depends on whether the material is being used for exploratory reactions, building-block libraries, or a route that is moving toward process development.
For process work, I place greater emphasis on lot consistency, impurity profiles, packaging, and supply continuity. A material that performs well in a small reaction may still require additional qualification before a larger batch is used. Buyers should request a representative sample, compare analytical results with their internal methods, and discuss whether the supplier can support repeat orders under the same or an agreed specification.
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The hydroxymethyl group offers a potential point for derivative preparation, while the boronic acid offers a separate reaction handle. This combination can be valuable for designing related intermediates, but the actual sequence must be validated experimentally. I recommend confirming compatibility with protecting groups, bases, oxidants, catalysts, and purification conditions during the early screening stage.
My selection process begins with identity verification. I compare the supplier’s product name, CAS number, structure, formula, and molecular weight, then check whether the proposed material is the intended para-substituted compound rather than a positional isomer. If the structure is not shown clearly, I request a structural representation or specification document before proceeding.
Next, I define the quality requirement according to the application. A research screening project may prioritize availability and a suitable sample size, while a process-development project may require tighter impurity controls, repeated lot supply, and more complete documentation. I also ask whether the quoted material is a standard product, made to order, or subject to current stock availability.
I also recommend requesting a small evaluation quantity, such as 1–5 g, when the project is still at the screening stage. This is a purchasing recommendation, not a universal packaging standard, because sample availability depends on supplier inventory and commercial terms. For larger requirements, buyers should ask for a production or dispatch plan in business days rather than relying on an informal availability statement.
The price of 4-(Hydroxymethyl)phenylboronic acid can vary with purity, quantity, packaging, stock status, analytical requirements, and destination. A low unit price may not represent the lowest total procurement cost if the supplier cannot provide documentation, consistent lots, or reliable export support. I compare the full quotation, including packaging, shipping terms, sample charges, and any requested testing.
Minimum order quantity and lead time should be confirmed specifically for the required grade. In-stock laboratory quantities and custom or larger-scale quantities may follow different schedules. Buyers should also ask how the supplier manages changes in raw materials, batch release, packaging, and repeat supply, because these factors influence project continuity.
When comparing suppliers, I look for clear technical communication and a willingness to answer specification-level questions. The supplier should be able to distinguish between a general product listing and a lot-specific quality document. I also check whether the supplier can support export packaging, SDS provision, commercial documentation, and communication with the buyer’s purchasing or quality department.
Maison Chemical approaches this product from a B2B supply perspective, supporting buyers who need more than a basic catalog entry. We can discuss the intended application, requested grade, quantity, documentation, and destination before preparing a quotation. Where appropriate, I recommend beginning with technical document review and sample evaluation so that the purchasing decision is based on evidence relevant to the buyer’s process.
The most reliable way to source 4-(Hydroxymethyl)phenylboronic acid CAS 59016-93-2 is to verify identity first, define the application-specific quality requirement second, and evaluate a representative sample before committing to a larger purchase. Buyers should not select a supplier solely on a product title or headline price. The practical evidence is found in the specification, analytical documentation, sample performance, logistics, and ability to support repeat supply.
If you are preparing an inquiry, send Maison Chemical the required quantity, target purity, intended use, packaging preference, destination, and documentation requirements. We can then help clarify available material, sample options, MOQ, lead time, and quotation conditions. This structured approach gives your technical and purchasing teams a clearer basis for supplier approval and future procurement.
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