4-Methoxyphenylboronic acid, also called 4-anisylboronic acid, is an aromatic boronic acid used mainly as a building block in carbon–carbon bond-forming chemistry. It contains a para-methoxy-substituted phenyl group and a boronic acid functional group that can participate in Suzuki–Miyaura coupling reactions with suitable aryl or vinyl halides. The compound is identified by CAS number 5720-07-0 and has the molecular formula C7H9BO3, with a molecular weight of approximately 151.96 g/mol.
At Maison Chemical, I supply 4-Methoxyphenylboronic acid for research, process development, and manufacturing applications where consistent identity, documentation, packaging, and supply continuity are important. Its practical value is not that it is a finished product, but that it provides a useful para-methoxyphenyl fragment for synthetic routes in pharmaceutical, agrochemical, materials, and fine chemical research.
The molecule combines an electron-rich anisole-type aromatic ring with a boronic acid group. The methoxy group is positioned at the 4-position relative to the boronic acid functionality, which is why the material is commonly described as 4-methoxyphenylboronic acid or 4-anisylboronic acid. This substitution pattern can influence the reactivity and selectivity of the intermediate in a planned synthetic sequence.
The boronic acid group is the main functional handle. Under suitable palladium-catalyzed Suzuki–Miyaura coupling conditions, it can react with aryl, heteroaryl, or vinyl halides to form a new carbon–carbon bond. The exact reaction performance depends on the coupling partner, catalyst system, base, solvent, temperature, concentration, and work-up procedure, so I recommend confirming conditions through development-scale testing rather than assuming one universal protocol.
In pharmaceutical and medicinal chemistry, researchers may use this compound to introduce a methoxy-substituted aromatic ring into a target structure. It is particularly relevant when a synthetic route requires controlled assembly of a biaryl or aryl–heteroaryl framework. The final use depends on the complete molecular design and the reaction sequence selected by the development team.
In agrochemical and specialty chemical research, 4-Methoxyphenylboronic acid can serve as an intermediate for exploring substituted aromatic structures. It may also be evaluated in the preparation of functional molecules used in materials research, provided that the target structure and process chemistry are compatible with boronic acid coupling chemistry.
For process chemists, the material can be valuable during route comparison. A buyer may evaluate it not only by unit price, but also by assay, impurity profile, particle characteristics, packaging, lot consistency, and the availability of technical documentation. These factors can affect reaction reproducibility and downstream purification requirements.
Commercial material is generally supplied as a solid powder, commonly described as white to off-white, although the exact appearance can vary with particle size, moisture exposure, storage history, and manufacturing conditions. Appearance alone is not sufficient for release decisions. I recommend using the supplier’s current certificate of analysis and agreed specification as the basis for acceptance.
| Item | Reference information | Why it matters |
|---|---|---|
| Product name | 4-Methoxyphenylboronic acid | Confirms the intended chemical building block |
| CAS number | 5720-07-0 | Supports identity checks and purchasing communication |
| Molecular formula | C7H9BO3 | Useful for calculations and analytical confirmation |
| Molecular weight | Approximately 151.96 g/mol | Required for molar quantity and reaction-charge calculations |
| Physical form | Solid powder; confirm current lot description | Helps define packaging, handling, and sampling expectations |
Depending on the application, a buyer may request assay by an appropriate analytical method, water or moisture information, residual solvent data, elemental impurity information, and a defined impurity profile. I do not recommend treating a generic purity statement as a complete quality assessment. For regulated or scale-up work, the specification should be agreed before ordering and connected to the buyer’s internal release procedure.
As with other fine chemical intermediates, I advise customers to handle 4-Methoxyphenylboronic acid according to the applicable safety data sheet, site procedures, and local regulations. Personnel should use appropriate laboratory or plant controls, including suitable protective equipment and measures that limit dust generation. The product should not be handled casually simply because it is supplied as a solid research chemical.
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Storage conditions should be selected using the supplier’s current technical and safety documentation. In general, buyers should keep the material tightly closed, protected from contamination and excessive moisture, and stored in a controlled area appropriate for the product classification. Before use, the production or research team should inspect the container, verify the label and lot number, and check whether the material meets the agreed release criteria.
Boronic acids can be sensitive to reaction conditions, moisture balance, and prolonged storage conditions in ways that depend on the specific structure and formulation. For this reason, I recommend confirming the material’s condition before charging a valuable reaction and retaining a representative sample where internal quality procedures require it. Any unusual color, caking, damaged packaging, or analytical deviation should be investigated rather than ignored.
The right supplier is the one that can match the required quality level and delivery model, not simply the one offering the lowest quoted price. I suggest beginning with the intended use: route screening, laboratory synthesis, pilot production, or recurring commercial manufacturing. The required documentation, packaging size, lead time, and quality controls can differ substantially between these scenarios.
For early-stage research, a smaller package may reduce inventory exposure and allow the chemist to confirm reaction suitability. For production planning, the buyer should also evaluate batch size, manufacturing capacity, change-control communication, and the supplier’s ability to provide consistent documentation. These checks can reduce the risk of selecting a material that works in a small experiment but creates avoidable problems during scale-up.
At Maison Chemical, I support B2B buyers by clarifying product identity, intended use, specification expectations, packaging needs, and delivery requirements before quotation. I can help organize a request around the CAS number, target quantity, required grade, destination, and documentation package. This allows our team to determine whether the request is suitable for a standard supply arrangement or requires additional technical discussion.
Our support may include product documentation coordination, packaging assessment, shipment planning, and communication regarding repeat procurement. Where a customer has a defined internal specification, I recommend sharing it during the inquiry stage so that the proposed material can be evaluated against the actual application rather than against a generic product description.
4-Methoxyphenylboronic acid CAS 5720-07-0 is a boron-containing aromatic intermediate used principally to introduce a 4-methoxyphenyl group into more complex molecules. Its most recognized role is as a coupling partner in suitable Suzuki–Miyaura reactions, although successful use depends on the complete reaction system and the customer’s target route. The compound has the reference formula C7H9BO3 and an approximate molecular weight of 151.96 g/mol.
For procurement, I recommend verifying identity, lot-specific quality data, packaging, safety documentation, storage expectations, MOQ, lead time, and repeat-supply capability. Buyers should select a specification that matches the development stage and intended process rather than relying on a single headline purity value. These steps provide a more reliable basis for laboratory evaluation, route development, and ongoing B2B supply.
In direct answer to the question, 4-Methoxyphenylboronic acid CAS 5720-07-0 is a specialized organic boronic acid intermediate used mainly for constructing substituted aromatic carbon–carbon bonds, especially in Suzuki–Miyaura coupling chemistry. It is useful when a project needs a para-methoxyphenyl building block, but its suitability must be confirmed through reaction-specific development and quality review. The most important buying decision is to match the material specification and supply model to the intended application.
To request a quotation from Maison Chemical, please provide the required quantity, application stage, target specification, packaging preference, destination, and documentation requirements. I can then help assess the appropriate supply route, clarify available support, and prepare a practical B2B response for your project.
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